What is Treatment-Resistant Depression - leawood kansas - aspkc - ketamine - tms

What is Treatment-Resistant Depression?

If you know someone who has been treated for depression but the symptoms have not improved, he/she is suffering from treatment-resistant depression. When a person suffers from treatment-resistant depression, antidepressants or standard treatments are not enough.

Features of TRD

Oftentimes, cases of depression where the patient displays some psychotic symptoms like hallucinations or delusion are more likely to fall into treatment-resistant depression. Similarly, another feature of TRD is the longer duration of intense depressive episodes.

Not to mention, patients having more severe or chronic depression, including the ones being suicidal, are more likely

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Transcranial Magnetic Stimulation and the Non-invasive Stimulation of Brain - leawood kansas - APSKC

Transcranial Magnetic Stimulation and the Non-invasive Stimulation of Brain

Transcranial Magnetic Stimulation was introduced in 1989 but until recently, rTMS or repetitive Transcranial magnetic stimulation was just a little-known method of stimulating our brain, non-invasively.

However, in 1995, the demonstration of rTMS possible and effective therapeutic effects on depression marked an increased interest among neurologists, psychiatrists, public and basic scientists.

So how does this well-recognized procedure stimulate the human brain and help in the treatment of chronic depression?

To discuss this, let us dig deeper into TMS principles!

Transcranial Magnetic Stimulation uses the inductance principle to provide electrical energy all across the human

Ketamine IV Administration and 100% Bioavailability

Ketamine IV Administration and 100% Bioavailability

Any patient who is new to Ketamine therapy must be anxious to know more about its working and how this whole process works!

Patients must know that Ketamine treatment is provided as an outpatient procedure. In other words, there is absolutely no need for lengthy or stressful hospital stays. Also, most of the Ketamine clinics don’t even ask for a referral to treat a new patient.

All they do is to conduct an interview to learn more about the history of the patient so that they can move forward with the treatment.


Antidepressants – Are They More Effective Than TMS - ketmaine KC - kansas city mo - leawood ks

Antidepressants – Are They More Effective Than TMS?

The psychiatric medication produces both beneficial as well as frustrating results. The statement is consistent with the STAR*D study. It is a large multi-center study with regards to the treatment of depression. The study was sponsored by the renowned Natural Institute of Mental Health.

This is a definitive study that involved thousands of patients and just one in every three patients was able to reach remission after their first attempt of antidepressant drug. Furthermore, it indicated that with every successive attempt, the rate of response decreased significantly while increasing the probability

Ketamine for Depression- Intranasal Vs- IV Infusion- ketamine kc - apskc - leawood ks - kansas city - tms

Ketamine for Depression: Intranasal Vs. IV Infusion

No doubt ketamine is the most proven and effective treatment to treat depression. Many studies have shown the potential of intravenous ketamine in improving the symptoms of depression in about 70% of individuals.

While ketamine IV infusions have remarkably known as the ‘gold standard’ in terms of administration, latest studies also discovered some other administration routes including sublingual, intramuscular and intranasal.

Intramuscular Administration

This administration route has raised some concerns because the administration rate is not as precise as needed for comfort and safety. In this process, ketamine absorbs quite rapidly into patient’s

Ways to Alleviate Depression Symptoms - ketamine kc - leawood ks

Ways to Alleviate Depression Symptoms

There are so many wonderful people in this world who miserably struggle with chronic depression. Studies show, that the effects of depression for each person are different. Oftentimes, what treatment works for one, may not work for another.
You must have seen how debilitating effects of depression take away pleasure from patients’ daily lives.
It may also cause isolation, lower self-esteem that complicates relationships, work performance and may lead to several other ailments.
Thus, to help these people alleviate the devastating effects of depression, let us identify some of the ways that can

Brain Function and Ketamine – How it Works - ketamine kc - aspkc - leawood ks - kansas city mo

Brain Function and Ketamine – How it Works

It’s been a long time since we have watched the successful progression of ketamine to treat the patients suffering from psychiatric disorders. In fact, we’ve always known its effectiveness to eliminate anxiety, depression, bipolar disorder and even PTSD.


So what makes ketamine so effective and how it works in our brain?

So far many researchers have attempted to unveil this mystery. These researchers have come upon many different potential uses for IV infusions including pain relief, elimination of suicidal ideations, prevention of relapse in drug abuse and alcohol etc.

Also, little by little,

Female Doctor Checking Patients Pulse

What Are Additional Tests Conducted Before Ketamine Infusion Therapy?

As we know ketamine is an anesthetic drug that is effectively and safely used in hospitals worldwide. The drug is now also used in sub-anesthetic dosage to treat chronic depression in people belonging to different age groups.

Before you receive the ketamine infusion therapy, there are some additional test administered by your psychiatrist to finally ascertain if you meet the exclusion/inclusion criteria. These additional tests include;

Patient Health Questionnaire-9 (PHQ-9)

The PHQ-9 is actually a 1-2 minutes brief and self-administered test. It is conducted to measure the depression severity in the patient and

Is There An Evidence Of Transcranial Magnetic Stimulation For The Treatment Of Chronic Depression

Is There An Evidence Of Transcranial Magnetic Stimulation For The Treatment Of Chronic Depression?

Since its introduction, Transcranial Magnetic Stimulation – TMS has been tested through different studies for its efficacy in treating major depression. There are many clinical trials (more than 20) that prove this treatment to be a successful brain stimulation method.

Brain stimulation techniques are the only treatment modality that can possibly be used to treat the patients with treatment-resistant depression. This is exactly what was proven through various controlled and randomized trials which investigated the potential of rTMS to treat chronic depression.

To give you an example;

Toro, et al. studied the rTMS

brain- tms - ketamine kc - aspkc - leawood -ks-mo-kansas city

TMS – A non-invasive method that is changing the modern medicine practices

The transcranial magnetic stimulation has greatly contributed to understanding the function of a normal brain. It also helps in stimulating the human brain and nerves for therapy. In other words, the growth of this non-invasive method has now fundamentally shifted the modern medicine practices!

By the use of nuclear magnetic resonance imaging to electrocardiograms, many clinicians are constantly acquiring complete and better understanding of things happening inside the human body.

This is being done without the need for surgery or having to cut open the body. With that, TMS also provides an