Alzheimer

Current Development to Treat Alzheimer’s disease

Aberrant processing with regards to protein – amyloid precursor, which leads to increased aggregation and production of the β amyloid peptide in the human brain, is believed to be the basis of pathogenesis of diseases like Alzheimer’s.   Whereas β amyloid peptide is cut from within the amyloid precursor by two basic enzymes called γ-secretase and β secretase, one successful strategy of treatment for Alzheimer’s disease is to decrease the making of β amyloid by inhibiting all these secretases.   Is there any...